proband
/ˈprəʊbənd
/noun Medicine & Genetics
A person serving as the starting point for the genetic study of a family.Furthermore, all these approaches are unable to handle trios with missing genotypic information on the proband and these families are typically excluded from the analysis....
- A genetic basis to the disorder is borne out by risk increasing with genetic proximity to the proband.
- Most data sets utilized in the study of hereditary diseases are constructed around probands, making correction for ascertainment bias necessary; this set of data is no exception.
Origin
1920s: from Latin probandus 'to be proved', gerundive of probare 'to test'.
- rose-breasted robin
- rose breccia
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- rosebud
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- rose cold
- rose color
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- rose-colored cockatoo
- rose-colored pastor
- rose-colored spoonbill
- rose-colored vervain
- rose colour
- rose-coloured
- rose-coloured cockatoo
- rose-coloured pastor
- rose-coloured spoonbill