methotrexate
/ˌmɛθəˈtrɛkseɪt
/ /ˌmiːθəˈtrɛkseɪt/noun [mass noun] Medicine
A synthetic compound that interferes with cell growth and is used to treat leukaemia and other forms of cancer.
- Chemical formula: C20H22N8O5.
- Treatment may include systemic steroids, intralesional steroid injection, antimalarials, or methotrexate.
- Antimalarial drugs or immune response modifiers like methotrexate can reduce steroid dose and side effects.
Origin
1950s: from meth- (denoting a substance containing methyl groups) + elements of unknown origin.
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