anxious, disturbed, perturbed, troubled, bothered, distressed, concerned, upset, distraught, worried sick, disquieted, uneasy, ill at ease, fretful, fretting, agitated, in a state of agitation, nervous, edgy, on edge, like a cat on a hot tin roof, tense, overwrought, worked up, keyed up, strung out, jumpy, with one's stomach in knots, stressed, under stress;

distracted, apprehensive, fearful, afraid, frightened, scared, with one's heart in one's mouth, quaking, trembling, shaking in one's shoes, in a cold sweat

informal uptight, a bundle of nerves, on tenterhooks, with butterflies in one's stomach, hassled, jittery, twitchy, in a state, wired, in a stew, in a dither, all of a dither, in a flap, in a sweat, in a tizz/tizzy, all of a lather, het up, in a twitter, rattled

British informal strung up, stressy, windy, having kittens

North American informal antsy, spooky, spooked, squirrelly, in a twit

Australian/New Zealand informal toey

British vulgar slang shitting bricks, bricking oneself

dated overstrung, unquiet