单词	psychotomimetic
释义	psychotomimetic /sʌɪˌkɒtə(ʊ)mɪˈmɛtɪk / adjective Relating to or denoting drugs which are capable of producing an effect on the mind similar to a psychotic state: such altered states of consciousness follow ingestion of LSD and other psychotomimetic drugs... In animal models 5 - HT2 antagonists (ketanserin and spiperone) were shown to block the psychotomimetic effects of both LSD and DOM. LSD was a synthetic drug, based on a naturally produced substance, which is called psychotomimetic drugs, made out of this rust. There is no clinically tested antidote available to antagonize the psychotomimetic symptomatology induced by PCP. noun A psychotomimetic drug.LSD - 25, used as a psychotomimetic, allows us to study these problems of communication from the inside and learn how to devise better methods of helping the sick.... High potency as an antagonist of 5-HT in isolated smooth muscle preparations was not correlated with high potency as a psychotomimetic. The hypothesis that psychotomimetics induce a rapid dopamine receptor regulation that could participate in the expression of the brain dopaminergic overactivation and in the early signs of psychotic-like behaviour, was checked by radioligand binding on rat brain cryosections.
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