dideoxyinosine
/ˌdʌɪdɪɒksɪˈɪnəʊsiːn
/(abbreviation DDI or ddI)
noun [mass noun] Medicine
A drug which inhibits the replication of HIV and is used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analogue of a purine nucleoside.We have now extended these studies to investigate the induction of mutants and micronuclei in mice treated neonatally with ddI or ddI in combination with AZT....
- In January 2001 the Food and Drug Administration issued a special warning to pregnant women taking nucleoside analogues ddI and d4T after three women died.
- A much publicized case in point is that of didanosine or ddI, a key antiretroviral patented by the US-based drug transnational Bristol-Myers Squibb.
Origin
1970s: from di-1 'two' + deoxy- (in the sense 'that has lost oxygen') + inosine.
- periodate
- period costume
- period doubling
- periodic
- periodic acid
- periodic acid–Schiff
- periodical
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- periodically
- periodical month
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- periodic comet
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- periodic function
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- periodic table
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- periodise