dideoxyinosine
/ˌdʌɪdɪɒksɪˈɪnəʊsiːn
/(abbreviation DDI or ddI)
noun [mass noun] Medicine
A drug which inhibits the replication of HIV and is used in the treatment of AIDS, especially in combination with zidovudine. It is a synthetic analogue of a purine nucleoside.We have now extended these studies to investigate the induction of mutants and micronuclei in mice treated neonatally with ddI or ddI in combination with AZT....
- In January 2001 the Food and Drug Administration issued a special warning to pregnant women taking nucleoside analogues ddI and d4T after three women died.
- A much publicized case in point is that of didanosine or ddI, a key antiretroviral patented by the US-based drug transnational Bristol-Myers Squibb.
Origin
1970s: from di-1 'two' + deoxy- (in the sense 'that has lost oxygen') + inosine.
- as near as damn it
- (as) nice (or sweet) as pie
- a snowball's chance (in hell)
- (as) nutty as a fruitcake
- asocial
- (as) of right (or by right)
- as often as not
- Asoka
- Asoka Chakra
- Asoka pillar
- as old as the hills
- as one door closes, another opens
- as one man
- a song and dance
- as opposed to
- as (or so) far as it goes
- as (or so) far as —— is concerned
- as (or so) long as
- as (or so) the saying goes (or is)
- as (or when or where) the fancy takes one
- asp
- a spanner (or monkey wrench) in the works
- asparagine
- asparagus
- asparagus beetle