nalidixic acid
/ˌnalɪˈdɪksɪk
/noun [mass noun] Medicine
A synthetic compound which inhibits the multiplication of bacteria, used chiefly to treat urinary infections.
- A heterocyclic compound; chemical formula: C12H12N2O3.
- The original quinolone antibiotics included nalidixic acid, cinoxacin and oxolinic acid (no longer available in the United States).
- There has also been a change in the antimicrobial susceptibility pattern; resistance to ampicillin and nalidixic acid has changed in recent times.
Origin
1960s: nalidixic by rearrangement of elements from naphthalene, carboxylic, and di-1 (forming the systematic name).
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