neocarzinostatin
/ˌniːə(ʊ)ˌkɑːzɪnə(ʊ)ˈstatɪn/Pharmacology
noun
A compound with antibiotic and antineoplastic properties, obtained from a strain of Streptomyces bacteria (sometimes called Streptomyces carzinostaticus), and consisting of a sulphur-containing apoprotein with a non-protein chromophore group that binds to and cleaves double-stranded DNA.
- The chromophore group of neocarzinostatin is an enediyne, containing a carbon-carbon double bond flanked by two carbon-carbon triple bonds..
Origin
1960s; earliest use found in Journal Antibiotics. From neo- + carzinostatin, an antineoplastic substance isolated from a Streptomyces strain from carzino- + -stat + -in.