单词	nephrotoxic
释义	nephrotoxic /ˌnɛfrə(ʊ)ˈtɒksɪk / adjective Damaging or destructive to the kidneys.The common potentially reversible causes are sepsis, excessive diuresis or paracentesis, and nephrotoxic drugs.... Several other drugs used in CF care have nephrotoxic and ototoxic potential. Critical measures include maintaining adequate intravascular volume and mean arterial pressure, discontinuing all nephrotoxic drugs, and eliminating exposure to any other nephrotoxins. Derivatives nephrotoxicity noun ... Nearly 40% of the patients had a creatinine clearance below normal, although there was no overt chronic nephrotoxicity. When examining the relationships between peak and trough vancomycin serum levels and the subsequent development of nephrotoxicity or ototoxicity, it is difficult to predict risk based on these data. Most of the rare reports of ototoxicity or nephrotoxicity in patients receiving vancomycin are complicated by concomitant illness or drug use associated with such side effects. nephrotoxin noun ... Management includes correction of fluid and electrolyte levels; avoidance of nephrotoxins; and kidney replacement therapy, when appropriate. Critical measures include maintaining adequate intravascular volume and mean arterial pressure, discontinuing all nephrotoxic drugs, and eliminating exposure to any other nephrotoxins. Conditions that place patients at risk for this condition include untreated prerenal azotemia and the use of nephrotoxic drugs or exposure to other nephrotoxins.
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