nucleolysis
/ˌnjuːklɪˈɒlɪsɪs/noun
1 Pathology and Biochemistry. The disintegration, dissolution, or disruption of cell nuclei; karyolysis. Also: the breakdown of nucleic acid molecules, especially by enzymatic activity.
2 Surgery. The destruction of a nucleus in the central nervous system. rare.
3 Surgery and Medicine. Destruction of the nucleus pulposus of an intervertebral disc, especially by the injection of an enzyme or chemical. Compare earlier chemonucleolysis.
Origin
1960s. From nucleo- + -lysis. Compare earlier nucleolytic.
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