单词	nucleophilic
释义	nucleophilic /ˌnjuːklɪə(ʊ)ˈfɪlɪk / adjective Chemistry (Of a molecule or group) having a tendency to donate electrons or react at electron-poor sites such as protons. Often contrasted with electrophilic.EO is a direct-acting mutagen that reacts with nucleophilic molecules, including DNA, causing gene mutation and chromosome deletions in somatic cells.... Methyl lithium is very reactive and acts as a nucleophilic methylating reagent to electrophilic functional groups, such as ketones. In the case of aldehydes and ketones containing carbonyl groups, the highly nucleophilic Grignard reagent contributes its electron pair to form a bond with the carbon atom. Derivatives nucleophile noun ... The reactions can involve either anionic nucleophiles such as iodide ion or neutral molecules such as amines. In a similar way, both hydroxide ions and water molecules may act as nucleophiles by reacting with alkyl halides to produce alcohols. Unlike hydrocarbon based aromatics, which react most readily with electrophiles, perfluoro-aromatics and heterocyclic ring systems react better with nucleophiles.
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