irritate, annoy, anger, vex, irk, nettle, pique, exasperate, infuriate, get on someone's nerves, rub up the wrong way, get/put someone's back up, ruffle someone's feathers, try someone's patience;

goad, provoke, bait, taunt, pester, harass, prick, prod, sting

informal aggravate, rile, niggle, hassle, bug, miff, peeve, get under someone's skin, get up someone's nose, hack off

British informal wind up, get at, nark, get across

North American informal ride

vulgar slang piss off

rare exacerbate, hump, rasp