oncogene
/ˈɒŋkə(ʊ)dʒiːn
/noun Medicine
A gene which in certain circumstances can transform a cell into a tumour cell.Thus the presence of p53 mutation may trigger precipitate the derailment of the cell cycle machinery, rendering cells susceptible to additional aberrations in other important oncogenes and tumour suppressor genes....
- Recent studies have been investigating these conditions for the presence of specific translocations and the expression of oncogenes and tumour suppressor genes.
- This mechanism has been shown to be operational in the case of various oncogenes and tumour suppressor genes.