单词	acetylate
释义	acetylate /əˈsɛtɪleɪt / verb [with object] (often as adjective acetylated) Chemistry Introduce an acetyl group into (a molecule or compound): the acetylated forms of chloramphenicol... Serotonin in this gland is acetylated, then methylated, forming melatonin. Histones (DNA packaging proteins) have lysine tails, which can be acetylated in a post-translational modification step. The N-terminal group was acetylated to reproduce the experimental conditions at which the protein was studied. Derivatives acetylation noun ... The acetylation of salicylic acid increased the potency of morphine by making the compound more soluble in brain fat and facilitating transfer across the blood brain barrier. This effect is consistent with the expected large reduction in electron density on the amino nitrogen upon acetylation thus making coordination with copper much less strong. Slowly, as researchers learned more about the structure of histones, it became evident that patterns of acetylation and methylation could be quite precise.
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