单词	penicillinase
释义	penicillinase /ˌpɛnɪˈsɪlɪneɪz / noun [mass noun] Biochemistry An enzyme which can inactivate penicillin, produced by certain bacteria: the potential to produce penicillinase [count noun]: resistant to penicillinases... For example, the resistance to penicillin initially was due to production of an enzyme penicillinase by bacteria, antibiotics like cloxallin were developed which was resistant to penicillinase enzyme. A control gene regulates the production of an enzyme that destroys the antibiotic, e.g. penicillinase which destroys penicillin. Penicillin was first used in the early 1940s and by 1950, most Staphylococcus aureus organisms were resistant to the drug by virtue of elaboration of a penicillinase enzyme.
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