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单词 biotransformation
释义

biotransformation

/ˌbʌɪəʊtransfəˈmɛɪʃ(ə)n / /trɑːns-/ /-nz-/
noun [mass noun]
The alteration of a substance, typically a drug, within the body.Medication clearance and excretion occur by two major mechanisms: hepatic metabolism or biotransformation and renal excretion....
  • It is unlikely to be a direct effect and is probably a result of biotransformation of the drug in the lung to reactive metabolites and/or oxygen species that damage lung cells.
  • Other recognized factors leading to medication allergy are pre-existing allergies and presence of diseases that interfere with medication biotransformation and excretion.
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更新时间:2024/11/14 21:12:23