Scatchard plot
/ˈskatʃɑːd
/noun Biochemistry
A plot of the concentration of a solute absorbed by a protein, membrane, cell, etc., against its concentration in the surrounding medium.To investigate whether the decrease in insulin binding was attributed to a decrease in the number of receptor sites per cell, the Scatchard plot for the data was analyzed....
- Previously, they were able to obtain Scatchard plots for the binding of RB - 5'-phosphate with albumin, but this experiment failed with RB because of the small binding constant.
- The presence of a single binding site per RyR was confirmed in the Scatchard plot, where the straight line was constructed using the same parameters as above.
Origin
1940s: named after George Scatchard (1892–1973), American physical chemist.
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