spermatogonium
/ˌspəːmətə(ʊ)ˈɡəʊnɪəm
/ /spəˌmatə(ʊ)ˈɡəʊnɪəm/noun (plural spermatogonia /ˌspəːmətə(ʊ)ˈɡəʊnɪə/ /spəˌmatə(ʊ)ˈɡəʊnɪə/) Biology
A cell produced at an early stage in the formation of spermatozoa, formed in the wall of a seminiferous tubule and giving rise by mitosis to spermatocytes.In severely degenerated tubules, only spermatogonia and Sertoli cells were observed, and pachytene spermatocytes sloughing into the lumen were observed....
- The primitive germinal cells are the spermatogonia, which lie peripherally in the tubule wall, outside the barrier of Sertoli cell junctions.
- In the testis, these cells are termed the spermatogonia.
Derivatives
spermatogonial
- Because they can now grow spermatogonial stem cells in culture, researchers have a ready source of cells that they could manipulate genetically, explained the study's senior author.
- A maximum of 50 offspring were tested from each ENU-treated male to prevent the recovery of identical mutations from the limited population of spermatogonial stem cells.
- At the apical end of the testes, stem cells divide to produce a spermatogonial cell that undergoes four rounds of mitosis to produce 16 primary spermatocytes.
Origin
Late 19th century: from sperm + modern Latin gonium (from Greek gonos 'offspring, seed').
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