单词	hypermutable
释义	hypermutable /hʌɪpəˈmjʊːtəb(ə)l / adjective Genetics Of or in a state in which mutation is abnormally frequent.After 60 cycles of single colony isolation, close to 30% of the lineages have a mutation at this hypermutable site.... As predicted by the fact that microsatellites are hypermutable, many flanking-sequence variants were associated with multiple repeat alleles. The situation of recurrent mutation is especially likely for a C / T polymorphism at the hypermutable CpG dinucleotides. Derivatives hypermutation noun ... For example, somatic hypermutation of Ig genes is used to generate antibodies with increased antigen affinity. Among the progeny, a variable proportion suffer hypermutation (C-to-T transitions) of both copies of the gene. The corresponding near-neighbors had to be removed because not all putative CG tandems are generated by CG hypermutation.
随便看	pluriarc pluricellular pluricentral pluricultural pluricuspid pluridentate pluridimensional pluri-disciplinary pluries pluriflorous plurifoliate plurifoliolate pluriform pluriformity plurify plurilingual plurilingualism plurilocular plurimodal plurinominal plurinucleate plurinucleated pluripara pluriparity pluriparous

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