spironolactone
/ˌspʌɪrənə(ʊ)ˈlaktəʊn
/noun [mass noun] Medicine
A steroid drug which promotes sodium excretion and is used in the treatment of certain types of oedema and hypertension.For example, ACE inhibitors, beta-blockers, ARBs, spironolactone and digoxin are probably not necessary in all patients....
- Pharmacologic agents used have included hydrochlorothiazide, spironolactone, furosemide, propranolol, or hydralazine.
- We restricted our analyses to loop diuretics, angiotensin converting enzyme inhibitors, blockers, spironolactone, and digoxin.
Origin
1960s: from spiro-1 (sense 2) + lactone, with the insertion of -one.