macroglobulinaemia
/ˌmakrəʊˌɡlɒbjʊlɪˈniːmɪə/(also macroglobulinemia) Pathology
noun
An increased level of macroglobulins, especially of immunoglobulin M, in the blood; specifically (more fully Waldenström's macroglobulinaemia British/ˈvaldənʃtrəːmz/ U.S./ˈwɑldənstrɑmz//ˈvɑldənʃtrəmz/) a lymphoproliferative disorder affecting chiefly the bone marrow and the reticuloendothelial system, characterized by the presence of monoclonal immunoglobulin M (or, rarely, IgG or IgA).
Origin
1940s. From German Makroglobulinämie from Makroglobulin + -ämie. The condition was earlier described by Waldenström in 1944, in Acta Med. Scandinavica 117 216.
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