substantific
/ˌsʌbst(ə)nˈtɪfɪk/adjective
That produces substance; that substantifies.
- Frequently in substantific marrow: the vital centre, the essence (from Rabelais' Gargantua)..
Origin
Mid 17th century; earliest use found in Thomas Johnson (d. 1644), apothecary and soldier. From (i) Middle French, French †substantifique essential, vital.