supercoil
/ˈsuːpəkɔɪl
/Biochemistry
noun
another term for superhelix.A proposed geometry of the LacI loop as a tight supercoil away from the protein has been controversial, and it is likely that loop geometry is different for different DNA sequences....
- Its major biological role in the bacterial cell is the removal of excessive negative supercoils from DNA to maintain the DNA at optimal superhelical density along with DNA gyrase.
- This characteristic pattern of plateaus and jumps is observed using Drosophila melanogaster Topo II demonstrating that this enzyme simultaneously binds to the G- and T-segments and stabilizes plectonemic supercoils.
verb [with object]
Form (a substance) into a superhelix: (as adjective supercoiled) a supercoiled circular DNA molecule...
- Extensions from linear to circular supercoiled DNA were subsequently reported, including improvements that extended the coverage from low salt to physiological salt conditions.
- Chromosomes are visible only during cell division, when the DNA is supercoiled and condensed to facilitate distribution into daughter cells.
- Interestingly, the structure of the H-NS-DNA complex alone permits the nucleoid to respond, with high sensitivity, to changes in temperature and osmolarity, independent of additional host proteins and changes in DNA supercoiling.
- Becket, St Thomas à
- Beckettian
- Beckett, Samuel
- Beckford, William
- Beckham, David
- Beckmann, Ernst Otto
- Beckmann, Max
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