Arising from or marked by despair or loss of hope "a despairing view of the world situation"; "the last despairing plea of the condemned criminal" - desperate
Verb: despairdi'spehr
Abandon hope; give up hope; lose heart "Don't despair--help is on the way!"
See also: despairingly, desperate, desperation, hopeless
Antonym: hope
Encyclopedia: Despair Despair, Inc Despair, The torn heart