1. Definitely not
   "the prize is by no means certain"
   - not by a long sight, not by a blame sight

Antonym: by all means

• twenty-one
• twenty-second
• twenty-seven
• twenty-seventh
• twenty-six
• twenty-sixth
• twenty-third
• twenty-three
• reprice
• reprieve
• reprimand
• reprint
• reprinting
• reprisal
• reprise
• reprize
• repro
• reproach
• reproacher
• reproachful
• reproachfully
• reprobate
• reprobation
• reprocess
• reproduce