1. Marked by excessive self-indulgence and moral decay
   "a group of effete self-professed intellectuals"
   - decadent 
2. Lacking in power or forcefulness
   - ineffective, ineffectual, unable

See also: impotent, indulgent

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• 5-hydroxy-3-methylglutaryl-coenzyme A reductase
• 5-hydroxytryptamine
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