1. A fatal form of homozygous thalassemia (inherited from both parents) in which there is no haemoglobin; skeletal deformations; heart and spleen and liver enlarged
   - Cooley's anemia [N. Amer], thalassemia major [N. Amer], thalassaemia major [Brit, Cdn]

Type of: Mediterranean anaemia [Brit, Cdn], Mediterranean anemia [N. Amer], thalassaemia [Brit, Cdn], thalassemia [N. Amer]

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