1. Toward the source or against the current
   - upriver

1. In the direction against a stream's current 
2. In the direction towards the source of a signal; at a higher level
   "The messages are transmitted to dendrites by upstream neurons via synapses"

Antonym: downstream

Encyclopedia: Upstream

• federation of tribes
• federative
• Federative Republic of Brazil
• Federico Fellini
• federita
• fedora
• fee
• fee simple
• fee splitting
• fee-tail
• feeble
• feebleminded
• feeblemindedness
• feebleness
• feebly
• feed
• feed bunk
• feed grain
• feed in
• feed on
• feed upon
• feedback
• feedback circuit
• feedback loop
• feedbag