1. Indicating opposition or resistance
   - counter 
2. Characterized by antagonism or antipathy
   "slaves antagonistic to their masters"
   - antipathetic, antipathetical 
3. Arousing animosity or hostility
   "his antagonistic brusqueness"; "Europe was antagonistic to the Unites States" 
4. Used especially of drugs or muscles that counteract or neutralize each other's effect
   - incompatible 
5. Incapable of harmonious association

See also: alienating, antacid, antagonism, antagonist, antagonistically, antiphlogistic, hostile, incompatible, negative

Antonym: conciliatory, synergistic

Encyclopedia: Antagonistic

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