1. Burdened by cares
   "all ye that labour and are heavy-laden"
   - care-laden 
2. Bearing a physically heavy weight or load
   "a heavy-laden cart"
   - burdened, loaded down

See also: encumbered, troubled

• combretum family
• combtooth blenny
• comburant
• comburent
• combust
• combustibility
• combustible
• combustible material
• combustibleness
• combustion
• combustion chamber
• combustive
• come
• come a cropper
• come about
• come across
• come after
• come again
• come alive
• come along
• come apart
• come around
• come away
• come before
• come by