1. Burdened by cares
   "all ye that labour and are heavy-laden"
   - care-laden 
2. Bearing a physically heavy weight or load
   "a heavy-laden cart"
   - burdened, loaded down

See also: encumbered, troubled

• appointed
• appointee
• appointive
• appointment
• appointment book
• appointment calendar
• apportion
• apportionable
• apportioned
• apportioning
• apportionment
• apposable
• appose
• apposite
• appositely
• appositeness
• apposition
• appositional
• appositive
• appositively
• appraisal
• appraise
• appraisee
• appraisement
• appraiser