a knockout blow
an event or action that causes someone or something to fail:
Already out of training, the latest illness has dealt her hopes of a gold medal a knockout blow.
Thesaurus: synonyms and related words
Accidents and disasters
- accident
- accidental
- accidentally
- accidentally on purpose idiom
- accidents will happen idiom
- calamity
- cataclysm
- catastrophe
- debacle
- devil
- disastrous
- emergency
- forest fire
- holocaust
- knockout
- meltdown
- misadventure
- snafu
- the devil to pay idiom
- tragedy
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