Oricula Therapeutics – Developing medications to protect hearing and balance from the effects of aging and ototoxic drugs, or medications that are toxic to the ear.

Disruption of the sensory hair bundle by genetic mutation, loud sounds, or ototoxic drugs can lead to hair-cell dysfunction and deafness. 

The resulting expression stimulated regeneration of spiral ganglion neurites, which had atrophied 2 weeks after ototoxic treatment, in a bilateral sensorineural deafness model.