large-eyed \ˈ ̷ ̷| ̷ ̷\adjective 1.: having large eyes < a large-eyed shrimp > or a large eye < large-eyed darning needles > 2. a.: having the eyes wide open in or as if in interest, curiosity, or amazement < gave a shy large-eyed glance > b.: of a kind or degree to make the eyes open wide < waiting in large-eyed wonder >