an·ti·chris·tian I. \| ̷ ̷(ˌ) ̷ ̷|-\adjective Etymology:anti- (I) + Christian 1.: of or relating to an antichrist 2.: opposed to or rejecting Christ or Christianity • an·ti·chris·tian·ism\| ̷ ̷(ˌ) ̷ ̷ˈ-\noun-s II. noun (-s) 1.obsolete: a follower of an antichrist 2.: one who is opposed to or rejects Christ or Christianity