de·naturalize \(ˈ)dē, də̇+\transitive verb Etymology:de- + naturalize 1.: to make unnatural : take away or alter the true or proper nature of : alienate from nature < it was landscape denaturalized … and with all that was left adapted to a decorative purpose — New York Herald Tribune > 2.[French dénaturaliser, from dé- de- (from Old French de-, des-) + naturaliser to naturalize]: to deprive of the rights and duties of a subject or citizen — opposed to naturalize