moleskin \ˈ ̷ ̷ˌ ̷ ̷\noun 1.: mole III 1d 2. a.: a heavy durable cotton fabric made in satin weave for industrial, medical, and clothing uses and usually with a smooth twilled surface on one side and a short thick velvety nap on the other b.: a garment (as trousers) made of moleskin — usually used in plural < got on their boots and moleskins — Mary S. Broome > 3.: mole III 4a