zyg- combining form orzygo- Etymology: New Latin, from Greek, from zygon — more at yoke 1. a.: yoke : connecting in the manner of a yoke : joining < zygosphene > < zygantrum > < zygoneure > b.: zygomatic < zygion > 2.: yoked state or part : pair < zygodactyl > < zygodont > 3.: union : fusion : zygosis < zygospore > < zygogenesis >