pap·il·lo·ma·to·sis \ˌ ̷ ̷ ̷ ̷ˌ ̷ ̷məˈtōsə̇s\noun (pluralpapillomato·ses \-ˌsēz\) Etymology: New Latin, from papillomat-, papilloma + -osis 1.: a condition marked by the presence of numerous papillomas 2.: a virus disease of various domestic and wild animals characterized by widespread development of warty tumors especially on the skin or in the mouth < papillomatosis of rabbits >