ephe·sian I. \ə̇ˈfēzhən, ēˈ-, eˈ- sometimes -zhēən\adjective Usage: usually capitalized Etymology: Latin Ephesius (from Greek Ephesios, from Ephesos Ephesus, ancient city of Asia Minor) + English -an : of or belonging to Ephesus II. noun (-s) 1.capitalized: a native or inhabitant of Ephesus 2.usually capitalized: a boon companion < it is thine host, thine Ephesian, calls — Shakespeare >