vicissitude /vi-sisˈi-tūd/

1. Change
2. Alternation
3. Mutation
4. Change of fortune (informal, for the worse)

vicissitūˈdinous adjective

• headlocks
• headlong
• head-lugged
• headman
• headmark
• headmarks
• headmaster
• headmasters
• headmastership
• headmasterships
• headmen
• headmistress
• headmistresses
• headmistress-ship
• headmistress-ships
• head money
• headmost
• headnote
• headnotes
• head off
• head of state
• head-on
• head over heels
• headpeace
• headphone