cofactor /kō-fakˈtər/

1. A factor which occurs along with other factors in multiplication
2. A nonprotein organic molecule or a metallic ion that binds with an enzyme and is essential to the enzyme's activity (biology)

• toplined
• topliner
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• toploftical
• toploftily
• toploftiness
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• toplofty
• topmaker
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• topman
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• top-notch
• top-notcher
• top-notchers
• topo