释义 |
stilbamidine Pharm.|stɪlˈbæmɪdiːn| [f. stilbene + amidine (f. amide + -ine5).] A diamidine derivative, (H2N)(HN)C·C6H4·CH:CH·C6H4·C(NH)(NH2), of stilbene which has antiprotozoal properties and has been used, usu. in the form of its isethionate, in the treatment of trypanosomiasis and leishmaniasis.
1941[see pentamidine]. 1958J. H. Burn Lect. Notes Pharmacol. (ed. 5) 110 Stilbamidine is no longer used [in the treatment of leishmaniasis] because it is toxic to the 5th nerve. 1977Jrnl. Pharmacol. & Exper. Therapeutics CCI. 555/1 Pentamidine, stilbamidine and their close analogs are known to interfere with nucleic acid and protein synthesis. |