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单词 stilbamidine
释义 stilbamidine Pharm.|stɪlˈbæmɪdiːn|
[f. stilbene + amidine (f. amide + -ine5).]
A diamidine derivative, (H2N)(HN)C·C6H4·CH:CH·C6H4·C(NH)(NH2), of stilbene which has antiprotozoal properties and has been used, usu. in the form of its isethionate, in the treatment of trypanosomiasis and leishmaniasis.
1941[see pentamidine].1958J. H. Burn Lect. Notes Pharmacol. (ed. 5) 110 Stilbamidine is no longer used [in the treatment of leishmaniasis] because it is toxic to the 5th nerve.1977Jrnl. Pharmacol. & Exper. Therapeutics CCI. 555/1 Pentamidine, stilbamidine and their close analogs are known to interfere with nucleic acid and protein synthesis.
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