| 释义 |
diazepam Pharm.|daɪˈæz-, daɪeɪzəpæm|
[f. benzodiazepine + -am, of unkn. origin.]
A minor tranquillizer of the benzodiazepine group with sedative, anticonvulsant, and amnesic properties, given orally and by injection to treat anxiety, muscle spasm, status epilepticus, etc., and sometimes giving rise to withdrawal symptoms when it is discontinued.
1961L. O. Randall et al. in Current Therapeutic Res. III. 405 (caption) Valium (LAIII) (diazepam). 1968[see Librium]. 1977Sci. Amer. Mar. 53/3 Alcohol, barbiturates and antianxiety drugs, such as chlordiazepoxide (Librium) or diazepam (Valium) seem to share brain mechanisms for tolerance and dependence. 1979Daily Tel. 29 Nov. 8/8 The big winner at the benzodiazipine tables has been the Swiss firm Roche, which introduced the first drug of this group, chlordiazepoxide, under the brand name Librium in 1960, followed by a variant, diazepam, brand named Valium, three years later. 1981M. C. Gerald Pharmacol. (ed. 2) xvi. 344 In 1977, 54 million prescriptions were written for diazepam. |