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单词 strophanthin
释义 strophanthin Pharm.|strəʊˈfænθɪn|
[f. strophanthus + -in1.]
Any or all of several polycyclic glucosides obtained from certain varieties of plants of the genera Strophanthus and Acokanthera and used as cardioactive drugs; G-strophanthin or g-strophanthin (also strophanthin-G, strophanthin-g) [L. g(rātus agreeable], the primary active component, C29H44O12, of the mixture obtained from S. gratus, A. schimperi, or A. ouabaio; also called ouabane; H-strophanthin, h-strophanthin, etc. [L. h(ispidus hairy], a mixture of the glucosides obtained from the seeds of S. hispidus; K-strophanthin, k-strophanthin, etc., [kombé], C36H54O14, the principle extract from S. kombe, also called kombé.
1873Pharm. Jrnl. III. 524/2 From this extract [of seeds of Strophanthus Hispidus, D.C.] Dr. Fraser succeeded in separating a very powerful active principle, which he proposes should be named strophanthin.1927Blackw. Mag. May 582/1 Strophanthin, its [sc. strophanthus'] laboratory derivative is a drug commonly used by the medical profession.1940Elsevier's Encycl. Org. Chem. Ser. III. XIV. 270, h-Strophanthin is a mixt. of glycosides from the seeds of Strophanthus hispidus.1960J. J. Lewis Introd. Pharmacol. xii. 356 Ouabain (G-strophanthin) is a crystalline glycoside obtained from S. gratus.1962H. L. Kern et al. in A. Pirie Lens Metabolism Rel. Cataract 389 The cardiac glycosides, gitalin and strophanthin K, produced effects [on the transport of potassium and anaerobic glycolysis in calf lens] comparable to ouabain.1978Acta Physiol. Acad. Sci. Hungaricae LI. 166 The therapeutic and toxic effects of strophanthin and digoxin on the heart were studied in the 6–7-week old human embryo.
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