释义 |
sulfa- altered and U.S. form of sulpha-, used to form the name of certain drugs (in British English sulpha- also occurs): sulfaˈmerazine (also -izine) [-mer + azine], the readily absorbed sulphonamide CH3·C4H2N2·NH·SO2·C6H4·NH2, now rarely used except in Sulphatriad; N1-(4-methylpyrimidin-2-yl)sulphanilamide; ˌsulfaquiˈnoxaline [quinoxaline], the sulphonamide C8H5N2·NH·SO2·C6H4·NH2, used as a coccidiostat in the treatment of cæcal coccidiosis in poultry; N1-quinoxalin-2-ylsulphanilamide.
1943A. D. Welch et al. in Jrnl. Pharmacol. & Exper. Therapeutics LXXVII. 357 The chemistry of this compound, which will be referred to as sulfamerizine, has been described in the publications of several groups. 1945Brit. Med. Jrnl. 3 Feb. 155/1 One new compound—sulphamerazine (or sulphamerizine)—has been the subject of much work in America. 1961A. Goth Med. Pharmacol. xli. 444 Sulfamerazine and sulfamethazine resemble sulfadiazine in most respects, except for the fact that they are excreted more slowly by the kidney. 1962J. H. Burn Drugs, Med. & Man xx. 200 Various new substances were prepared in this way, among them sulphathiazole, sulphadiazine and sulphamerazine. These compounds were not only different from sulphanilamide, but were much more potent. 1977Approved Names 1977 (Brit. Pharmacopœia Commission) 81 Sulfamerazine.
1944Jrnl. Biol. Chem. CLVI. 343 Recently, a new sulfonamide, sulfaquinoxaline, was introduced. 1961New Scientist 21 Dec. 742/1 Sulfaquinoxaline and sulfadimidine were administered to turkeys either in their food or by intramuscular injection. 1976Nature 17 June 621/2 The number of antagonists is now large, some of the best-known being.., sulphaquinoxaline and actinomycin D. 1977Approved Names 1977 (Brit. Pharmacopoeia Commission) 81 Sulfaquinoxaline. |