释义 |
Raynaud Med.|ˈreɪnəʊ| [The name of Maurice Raynaud (1834–81), French physician, who described various cases displaying Raynaud's phenomenon in 1862 (De l'Asphyxie Locale et de la Gangrène Symétrique des Extrémités).] Raynaud's disease or Raynaud's syndrome: an ill-defined disease or syndrome characterized by Raynaud's phenomenon, in which spasm of the arteries of the digits (often due to low temperature or vibration) leads to pallor, pain, and numbness, and in severe cases to gangrene.
1883Trans. Clin. Soc. XVI. 179, I have watched three cases which came within the category of Raynaud's disease. 1901J. Hutchinson in Med. Press & Circular CXXIII. 403/1 The expression ‘Raynaud's disease’ would imply that there is some one malady complete in itself, and having all the symptoms the same in all cases which is suitably denominated by that name. That is not the case. Ibid., I would rather speak of Raynaud's phenomena than of Raynaud's disease, for the former are things which we understand and are the same in all cases... What do we mean by Raynaud's phenomena?.. Local syncope, local asphyxia, symmetrical gangrene of the extremities are synonymous terms. 1925Raynaud's disease [see ganglionectomy]. 1932Amer. Jrnl. Med. Sci. CLXXXIII. 188 The increasing amount of literature attests to the tendency to utilize the terms ‘Raynaud's disease’ or ‘Raynaud's syndrome’ as a general depository for a heterogeneous group of cases far removed from the condition originally described by Raynaud. 1936Q. Jrnl. Med. XXIX. 399 For more than sixty years the term ‘Raynaud's disease’ was used as a convenient label for case after case of obscure aetiology in which pallor, cyanosis, pain, or gangrene of hands, feet, nose, or ears, happened to be symptoms, prominent or otherwise. Ibid. 401 ‘Raynaud's Phenomenon’ may, therefore, be defined as ‘Intermittent pallor or cyanosis of the extremities, precipitated by exposure to cold, without clinical evidence of blockage of the large peripheral vessels and with nutritional lesions, if present at all, limited to the skin’. 1937Raynaud's syndrome [see ganglionectomy]. 1946E. V. Allen et al. Peripheral Vascular Dis. vii. 185 The predilection of Raynaud's disease for the female is one of the outstanding etiological factors. Ibid. viii. 206 Raynaud's phenomenon may occur primarily as in Raynaud's disease or it can occur secondarily in association with a number of conditions and diseases. 1973Times 26 May 3/3 The name for the unusual affliction was Raynaud's Phenomenon, Mr Alan Lipfriend, Mr Lambert's counsel, told Mr Justice Mocatta. It was also known as vibratory white finger. The fingers went white, numb and stiff. 1975Daily Colonist (Victoria, B.C.) 18 Nov. 2/1 My doctor says I have Raynaud's disease... It is just like I am allergic to cold... My hands and feet are affected and hurt. |