| 释义 |
ethambutol, n. Pharm.|ɛˈθæmbjʊtɒl, -əʊl|
[f. ethyl n. + amino- + butanol n.]
A synthetic bacteriostatic compound used (usu. as the hydrochloride) in the treatment of tuberculosis; (S,S)-N,N′-ethylenebis(2-aminobutan-1-ol), C10H24N2O2 . Often used spec. of the laevoratory isomer.
1961Jrnl. Amer. Chem. Soc. LXXXIII. 2212/1 Ethambutol is the generic name reserved for this isomer by the Lederle Laboratories Division of the American Cyanamid Company. 1977Lancet 11 June 1232/1 Patients with bacteriologically positive pulmonary tuberculosis were treated initially for an average of three and a half months with isoniazid, rifampicin, and ethambutol. 1989Collier & Longmore Oxf. Handbk. Clin. Specialties (ed. 2) vi. 518 Ethambutol can have toxic effects upon the retina. |