| 释义 |
hypophysectomy Surg.|ˌhaɪpəʊfɪˈsɛktəmɪ|
[f. hypophysis + -ectomy.]
Excision of the hypophysis.
1909Reford & Cushing in Bull. Johns Hopkins Hosp. XX. 106/1 The effects of total canine hypophysectomy. 1939M. A. Goldzieher Endocrine Glands I. 270 Adult amphibia show atrophy of both ovaries and testes after hypophysectomy. 1962Lancet 15 Dec. 1235/1 Women with advanced breast cancer who subsequently fail to respond to adrenalectomy or hypophysectomy excrete significantly smaller amounts of urinary 11-deoxy 17-oxosteroids than do women who respond. 1967S. Taylor et al. Short Textbk. Surg. xv. 189 Adrenalectomy and hypophysectomy are being performed much less often now than a few years ago, because remissions are unpredictable and often short-lived.
Hence ˌhypophyˈsectomize v. trans., to deprive of the hypophysis, perform hypophysectomy on; usu. as ˌhypophyˈsectomized ppl. a.
1910Bull. Johns Hopkins Hosp. XXI. 131/1 Two of the partially hypophysectomized animals survived for 5 months. 1912H. Cushing Pituitary Body & its Disorders i. 11 Of a litter of three puppies..one, the largest, was partially hypophysectomized, one was fed daily..with powdered extract of the whole gland..: the third and smallest was kept as a control. 1934C. J. Wiggers Physiol. Health & Dis. (1935) lxvii. 1055 Hypophysectomized tadpoles neither grow nor metamorphose. 1936Jrnl. Path. & Bacteriol. XLII. 403 A tendency to maintenance of body weight after grafting of pituitary cultures into hypophysectomised rats has been taken as evidence of replacement of pituitary function. 1966W. S. Hoar in Harris & Donovan Pituitary Gland I. vi. 246 The Amphibians are relatively easy to hypophysectomize. 1970Nature 31 Oct. 464/2 Administration of growth hormone to hypophysectomized rats essentially prevented the appearance of any hypercholesterolaemia. |