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单词 Little's disease
释义 Little's disease Med.
[Named after William John Little (1810–94), English physician, who described it.]
Cerebral spastic paralysis of infants.
1885Boston Med. & Surg. Jrnl. CXII. 217/1 (heading) Cases of congenital muscular rigidity, or Little's disease.Ibid., This ‘congenital muscular rigidity’ was first described as an affection by Little, of London, in 1853, and Rupprecht..suggested that the name of Little's disease be applied to it.1887Buck's Handbk. Med. Sci. V. 200/2 Little's disease. Spasmodic tabes of children.1938Times Lit. Suppl. 22 Jan. 50/2 Recent researches would appear to have established that the trouble from which Byron suffered was not an ordinary club-foot: that he was the victim of some obscure nervous malady—Little's disease, otherwise spastic paraplegia, has been suggested.1964S. Duke-Elder Parsons' Dis. Eye (ed. 14) xxxiv. 549 Congenital spastic diplegia (Little's disease), a bilateral spastic paralysis present from birth, considered at one time to be due to meningeal hæmorrhage as a result of birth injury, is probably a degenerative cerebral process of obscure ætiology.
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