释义 |
long-term, a. [f. long a.1 + term n.] Lasting for, pertaining to, or involving a relatively long period of time; maturing or becoming effective only after a long period. Also quasi-advb.
1908Daily Chron. 24 July 1/6 The long-term men, who wore blue cotton overalls marked with the broad arrows, were in the rear. 1909Westm. Gaz. 2 June 5/2 Mr. Fielding was able to place a 2½ per cent., long-term loan in London. 1937Discovery June 178/1 A long-term programme of development. 1942C. S. Lewis Screwtape Lett. xiv. 73 It is His long-term policy..to restore to them a new kind of self-love. 1956C. Auerbach Genetics in Atomic Age 65 Thus each species has to strike a balance between the short-term requirement for a low frequency of mutation and the long-term requirement for an ample store of mutant genes. 1956Planning XXII. 38 The more specific the investment the greater the need for forecasting, especially long-term. 1959A. Lejeune Crowded & Dangerous xii. 134 The long-term future could look after itself. 1969Listener 5 June 786/3 The difficulty in getting both politicians and the bureaucracy to think long-term, particularly on financial affairs. 1971Jrnl. Gen. Psychol. LXXXV. 51 Short-term memory is required to act as..a cue to recall data from long-term storage. Ibid., The effectiveness of extracting information from long-term memory may depend on short-term load. 1972Accountant 23 Mar. 383/2 Valuation of long-term contracts. 1972Listener 21 Dec. 854/2 Courses of action are followed without regard for their long-term consequences. 1974Times 28 Dec. 9/6 Ordinary table wines..must not be kept long-term in the refrigerator.
▸ long-term potentiation n. Physiol. long-lasting enhancement of neurotransmission at a synapse following stimulation of the synapse under certain conditions, which is believed to be a cellular mechanism of plasticity (plasticity n. 2) in the brain and to be involved especially in learning and memory; abbreviated LTP.
[1973T. V. P. Bliss & T. Lømo in Jrnl. Physiol. 232331 (title) Long-lasting potentiation of synaptic transmission in the dentate area of the anaesthetized rabbit following stimulation of the perforant path.] 1975R. M. Douglas & G. V. Goddard in Brain Res. 86 205 (title) *Long-term potentiation of the perforant path-granule cell synapse in the rat hippocampus. 1992Economist 26 Dec. 119/1 This process, called long-term potentiation (LTP), happens when a particular neurotransmitter called glutamate is released by the axon side of a synapse and picked up on the dendrite side by a particular sort of receptor. 2001Business Week 11 June 96/2 [The company] is developing drugs that will help the brain convert transient short-term memories into stable long-term ones. This process, called long-term potentiation, is compromised in the aging brain and in Alzheimer's victims. |