| 释义 |
mengovirus, n. Biol.|ˈmɛŋgəʊvaɪrəs|
Also Mengo virus.
[f. the name of Mengo District, Buganda, Uganda, where the virus was first isolated.]
A picornavirus originally found in monkeys but capable of infecting other species, the infection in humans being characterized by encephalomyelitis.
[1948G. W. A. Dick et al. in Lancet 21 Aug. 286/1 Mengo encephalomyelitis virus was originally isolated from a paralysed rhesus monkey..which had been captive in the outside monkey runs in the compound of the Yellow Fever Research Institute in Entebbe.] 1949Jrnl. Immunol. LXII. 375 The UR 22 monkey strain..of Mengo virus was employed in these experiments. 1962Biochim. et Biophys. Acta LV. 241 These experiments suggest that mengovirus RNA may be synthesized in the cytoplasm. 1972Nature 18 Aug. 369/1 Early studies with vaccinia, mengovirus and Semliki Forest virus all indicated that interferon acts at a translation level. 1988Jrnl. Gen. Virol. LXXIX. 275 Interferon (IFN) response mutants were selected from mouse L929 fibroblast cells and their specific resistance to is-1, an IFN-sensitive mutant of mengovirus, were studied. |